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1

Cystic Fibrosis

Rowe, Steven M., Miller, Stacey, Sorscher, Eric J.

Journal:

Boston Medical and Surgical Journal

Year:

2005

Language:

english

File:

PDF, 543 KB

english, 2005

2

Respiratory Syncytial Virus Infection Disrupts Monolayer Integrity and Function in Cystic Fibrosis Airway Cells

Michele, Kong, Patrick, Maeng, Jeong, Hong, Rhonda, Szczesniak, Eric, Sorscher, Wayne, Sullender, Paul, Clancy

Journal:

Year:

2013

Language:

english

File:

PDF, 2.32 MB

english, 2013

3

The use of Trichomonas vaginalis purine nucleoside phosphorylase to activate fludarabine in the treatment of solid tumors

Parker, William B., Allan, Paula W., Waud, William R., Hong, Jeong, Gilbert-Ross, Melissa, Achyut, B. R., Joshi, Disha, Behbahani, Turang, Rab, Regina, Ealick, Steven E., Sorscher, Eric J.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2020

Language:

english

File:

PDF, 1.17 MB

english, 2020

4

Affinity purification of insoluble recombinant fusion proteins containing glutathione-S-transferase

John Hartman, Paru Daram, Raymond A. Frizzell, Thomas Rado, Dale J. Benos, Eric J. Sorscher

Journal:

Biotechnology and Bioengineering

Year:

1992

Language:

english

File:

PDF, 647 KB

english, 1992

5

Luminal fluid tonicity regulates airway ciliary beating by altering membrane stretch and intracellular calcium

György Horváth, Eric J. Sorscher

Journal:

Year:

2008

Language:

english

File:

PDF, 293 KB

english, 2008

6

Hepatocyte growth factor stimulates adenoviral-mediated gene transfer across the apical membrane of epithelial cells

Jason K. Burrus, William D. Matheson, Jeong S. Hong, Eric J. Sorscher, Daniel F. Balkovetz

Journal:

The Journal of Gene Medicine

Year:

2004

Language:

english

File:

PDF, 290 KB

english, 2004

7

Cigarette smoke condensate inhibits transepithelial chloride transport and ciliary beat frequency

Noam A. Cohen, Shaoyan Zhang, Dawn B. Sharp, Edwin Tamashiro, Bei Chen, Eric J. Sorscher, Bradford A. Woodworth

Journal:

The Laryngoscope

Year:

2009

Language:

english

File:

PDF, 326 KB

english, 2009

8

The bioflavonoid compound, sinupret, stimulates transepithelial chloride transport in vitro and in vivo

Frank Virgin, Shaoyan Zhang, Daniel Schuster, Christopher Azbell, James Fortenberry, Eric J. Sorscher, Bradford A. Woodworth

Journal:

The Laryngoscope

Year:

2010

Language:

english

File:

PDF, 302 KB

english, 2010

9

Exposure to cigarette smoke condensate reduces calcium activated chloride channel transport in primary sinonasal epithelial cultures

Frank W. Virgin, Christopher Azbell, Daniel Schuster, Jumin Sunde, Shaoyan Zhang, Eric J. Sorscher, Bradford A. Woodworth

Journal:

The Laryngoscope

Year:

2010

Language:

english

File:

PDF, 176 KB

english, 2010

10

Resveratrol has salutary effects on mucociliary transport and inflammation in sinonasal epithelium

Nathan S. Alexander, Neal Hatch, Shaoyan Zhang, Daniel Skinner, James Fortenberry, Eric J. Sorscher, Bradford A. Woodworth

Journal:

The Laryngoscope

Year:

2011

Language:

english

File:

PDF, 342 KB

english, 2011

11

Transepithelial ion transport is suppressed in hypoxic sinonasal epithelium

Angela Blount, Shaoyan Zhang, Michael Chestnut, Brian Hixon, Daniel Skinner, Eric J. Sorscher, Bradford A. Woodworth

Journal:

The Laryngoscope

Year:

2011

Language:

english

File:

PDF, 501 KB

english, 2011

12

Designer Gene Therapy Using an Escherichia coli Purine Nucleoside Phosphorylase/Prodrug System

Eric M Bennett, Ruchi Anand, Paula W Allan, Abdalla E.A Hassan, Jeong S Hong, Dana N Levasseur, David T McPherson, William B Parker, John A Secrist III, Eric J Sorscher, Tim M Townes, William R Waud,

Journal:

Chemistry & Biology

Year:

2003

Language:

english

File:

PDF, 494 KB

english, 2003

13

Correlation of microRNA levels during hypoxia with predicted target mRNAs through genome-wide microarray analysis

Jennifer S Guimbellot, Stephen W Erickson, Tapan Mehta, Hui Wen, Grier P Page, Eric J Sorscher, Jeong S Hong

Journal:

BMC Medical Genomics

Year:

2009

Language:

english

File:

PDF, 1.92 MB

english, 2009

14

Membrane transplantation to correct integral membrane protein defects

Kimberly V. Curlee, Jeong S. Hong, J. P. Clancy, Scott A. King, Eric Hunter, Bakhrom Berdiev, Dale Benos, Maja A. Sommerfelt, Eric J. Sorscher, Michael Sakalian

Journal:

Journal of Molecular Medicine

Year:

2003

Language:

english

File:

PDF, 465 KB

english, 2003

15

Clinical doses of amikacin provide more effective suppression of the humanCFTR-G542X stop mutation than gentamicin in a transgenic CF mouse model

Ming Du, Kim M. Keeling, Liming Fan, Xiaoli Liu, Timea Kovaçs, Eric Sorscher, David M. Bedwell

Journal:

Journal of Molecular Medicine

Year:

2006

Language:

english

File:

PDF, 367 KB

english, 2006

16

Is oncogenesis a normal cellular defense mechanism?

Steven Sorscher, Aubrey E. Hill, Eric J. Sorscher

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2008

Language:

english

File:

PDF, 117 KB

english, 2008

17

Evolutionary maintenance of oncogenesis

Steven M. Sorscher, Aubrey Hill, Eric J. Sorscher

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2009

Language:

english

File:

PDF, 173 KB

english, 2009

18

Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line

Bedwell, David M., Kaenjak, Anisa, Benos, Dale J., Bebok, Zsuzsa, Bubien, James K., Hong, Jeong, Tousson, Albert, Clancy, J.P., Sorscher, Eric J.

Journal:

Nature Medicine

Year:

1997

File:

PDF, 553 KB

1997

19

Antitumor activity of 2-fluoro-2′-deoxyadenosine against tumors that express Escherichia coli purine nucleoside phosphorylase

Parker, William B, Allan, Paula W, Hassan, Abdalla E A, Secrist, John A, Sorscher, Eric J, Waud, William R

Journal:

Cancer Gene Therapy

Year:

2003

Language:

english

File:

PDF, 153 KB

english, 2003

20

Failure of cAMP agonists to activate rescued ΔF508 CFTR in CFBE41o– airway epithelial monolayers

Zsuzsa Bebok, James F. Collawn, John Wakefield, William Parker, Yao Li, Karoly Varga, Eric J. Sorscher, J. P. Clancy

Journal:

The Journal of Physiology

Year:

2005

Language:

english

File:

PDF, 469 KB

english, 2005

21

Development of drug targeting based on recombinant expression of the chicken avidin gene

Walker, Lynn, Kulomaa, Markku, Bebok, Zsuzsa, Parker, William, Allan, Paula, Logan, James, Huang, Zhen, Reynolds, Robert, King, Scott, Sorscher, Eric

Journal:

Journal of Drug Targeting

Year:

1996

Language:

english

File:

PDF, 1.93 MB

english, 1996

22

Cystic fibrosis transmembrane conductance regulator modulation by the tobacco smoke toxin acrolein

Nathan S. Alexander, Angela Blount, Shaoyan Zhang, Daniel Skinner, Stephen B. Hicks, Michael Chestnut, Frederick A. Kebbel, Eric J. Sorscher, Bradford A. Woodworth

Journal:

The Laryngoscope

Year:

2012

Language:

english

File:

PDF, 340 KB

english, 2012

23

Severe phenotype in mice with termination mutation in exon 2 of cystic fibrosis gene

Paul Hasty, Wanda K. O'Neal, Karen-Qianye Liu, Andrew P. Morris, Zsuzsa Bebok, Gleb B. Shumyatsky, Tamas Jilling, Eric J. Sorscher, Allan Bradley, Arthur L. Beaudet

Journal:

Somatic Cell and Molecular Genetics

Year:

1995

Language:

english

File:

PDF, 2.56 MB

english, 1995

24

Hesperidin stimulates cystic fibrosis transmembrane conductance regulator–mediated chloride secretion and ciliary beat frequency in sinonasal epithelium

Christopher Azbell, Shaoyan Zhang, Daniel Skinner, James Fortenberry, Eric J. Sorscher, Bradford A. Woodworth

Journal:

Otolaryngology - Head and Neck Surgery

Year:

2010

Language:

english

File:

PDF, 1.12 MB

english, 2010

25

Hesperidin Stimulates Epithelial Cl- Secretion and CBF

Christopher Azbell, Shaoyan Zhang, Daniel Skinner, Eric Sorscher, Brad Woodworth

Journal:

Otolaryngology - Head and Neck Surgery

Year:

2010

Language:

english

File:

PDF, 42 KB

english, 2010

26

The non-random distribution of intronless human genes across molecular function categories

Aubrey E. Hill, Eric J. Sorscher

Journal:

Year:

2006

Language:

english

File:

PDF, 59 KB

english, 2006

27

Association of cystic fibrosis genetic modifiers with congenital bilateral absence of the vas deferens

Viktoria Havasi, Steven M. Rowe, Peter N. Kolettis, Didem Dayangac, Ahmet Şahin, Ana Grangeia, Filipa Carvalho, Alberto Barros, Mario Sousa, Lluis Bassas, Teresa Casals, Eric J. Sorscher

Journal:

Fertility and Sterility

Year:

2010

Language:

english

File:

PDF, 110 KB

english, 2010

28

Quercetin increases Cl-Transport in murine nasal epithelium

Nicholas J. Smith, Bradford Woodworth, Steven Rowe, Shaoyan Zhang, Eric Sorscher

Journal:

Otolaryngology - Head and Neck Surgery

Year:

2009

Language:

english

File:

PDF, 74 KB

english, 2009

29

Effects of megestrol acetate on weight gain, body composition, and pulmonary function in patients with cystic fibrosis

Valerie Eubanks, Nicki Koppersmith, Nancy Wooldridge, J.P. Clancy, Raymond Lyrene, Ramin B. Arani, Jeanette Lee, Lyle Moldawer, Joy Atchison, Eric J. Sorscher, Christopher M. Makris

Journal:

The Journal of Pediatrics

Year:

2002

Language:

english

File:

PDF, 93 KB

english, 2002

30

Assessment of CFTR localisation in native airway epithelial cells obtained by nasal brushing

Ceinwen M. Harris, Filipa Mendes, Anca Dragomir, Iolo J.M. Doull, I. Carvalho-Oliveira, Zsuzsanna Bebok, John P. Clancy, Valerie Eubanks, Eric J. Sorscher, Godfried M. Roomans, Margarida D. Amaral, Ma

Journal:

Journal of Cystic Fibrosis

Year:

2004

Language:

english

File:

PDF, 107 KB

english, 2004

31

Inhibitory effects of hypertonic saline on P. aeruginosa motility

Viktória Havasi, Casey O. Hurst, Travis C. Briles, Fan Yang, David G. Bains, Daniel J. Hassett, Eric Sorscher

Journal:

Journal of Cystic Fibrosis

Year:

2008

Language:

english

File:

PDF, 176 KB

english, 2008

32

Bioelectric effects of quinine on polarized airway epithelial cells

Eleanor Bates, Stacey Miller, Mariah Alexander, Marina Mazur, James A. Fortenberry, Zsuzsa Bebok, Eric J. Sorscher, Steven M. Rowe

Journal:

Journal of Cystic Fibrosis

Year:

2007

Language:

english

File:

PDF, 621 KB

english, 2007

33

Chinese Hamster Ovary Cell Mutants Deficient in an Anion Exchanger Functionally Similar to Erythroid Band 3

ADA ELGAVISH, JEFFREY D. ESKO, RAYMOND FRIZZELL, DALE BENOS, ERIC SORSCHER

Journal:

Annals of the New York Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 376 KB

english, 1989

34

In vivo antitumor activity of intratumoral fludarabine phosphate in refractory tumors expressingE. colipurine nucleoside phosphorylase

Sorscher, Eric J., Hong, Jeong S., Allan, Paula W., Waud, William R., Parker, William B.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2012

Language:

english

File:

PDF, 416 KB

english, 2012

35

DESIGN AND EVALUATION OF 5′-MODIFIED NUCLEOSIDE ANALOGS AS PRODRUGS FOR AN E. COLI PURINE NUCLEOSIDE PHOSPHORYLASE MUTANT

Parker, William B., Allan, Paula W., Ealick, Steve E., Sorscher, Eric J., Hassan, Abdalla E. A., Silamkoti, A. V., Fowler, Anita T., Waud, William R., Secrist, John A.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2005

Language:

english

File:

PDF, 112 KB

english, 2005

36

Marked repression of CFTR mRNA in the transgenic Cftrtm1kth mouse model

Zhang, Shaoyan, Ranganath, Neel K., Skinner, Daniel, Bedwell, David M., Buckley-Lanier, Jessica A., Sorscher, Eric J., Woodworth, Bradford A.

Journal:

Journal of Cystic Fibrosis

Year:

2014

Language:

english

File:

PDF, 204 KB

english, 2014

37

Development and Maintenance of a Biospecimen Repository for Clinical Samples Derived from Pulmonary Patients

Schwiebert, Lisa M., Estell, Kim, Meadows, Tonja, Thannickal, Victor J., Rowe, Steven, Sorscher, Eric J., Harris, W. Thomas, Gaggar, Amit, Dransfield, Mark, de Andrade, Joao A.

Journal:

Clinical and Translational Science

Year:

2014

Language:

english

File:

PDF, 331 KB

english, 2014

38

Characterization and Dynamics of Aggresome Formation by a Cytosolic GFP-Chimera

Rafael García-Mata, Zsuzsa Bebök, Eric J. Sorscher and Elizabeth S. Sztul

Journal:

The Journal of Cell Biology

Year:

1999

Language:

english

File:

PDF, 5.84 MB

english, 1999

39

Expression and Polarized Targeting of a Rab3 Isoform in Epithelial Cells

Edit Weber, Gabor Berta, Albert Tousson, Patricia St. John, Mary Weaver Green, Usha Gopalokrishnan, Tamas Jilling, Eric J. Sorscher, Terry S. Elton, Dale R. Abrahamson and Kevin L. Kirk

Journal:

The Journal of Cell Biology

Year:

1994

Language:

english

File:

PDF, 3.26 MB

english, 1994

40

Role for Phospholipid Interactions in the Trafficking Defect of ΔF508-CFTR †

Eidelman, Ofer, BarNoy, Shoshana, Razin, Michal, Zhang, Jiang, McPhie, Peter, Lee, George, Huang, Zhen, Sorscher, Eric J., Pollard, Harvey B.

Journal:

Year:

2002

Language:

english

File:

PDF, 948 KB

english, 2002

41

In Vivo Gene Therapy of Cancer with E. coli Purine Nucleoside Phosphorylase

Parker, William B., King, Scott A., Allan, Paula W., Bennett, L. Lee, Secrist, John A., Montgomery, John A., Gilbert, Karen S., Waud, William R., Wells, Alan H., Gillespie, G. Yancey, Sorscher, Eric J

Journal:

Human Gene Therapy

Year:

1997

Language:

english

File:

PDF, 2.88 MB

english, 1997

42

Antibiotic-Mediated Chemoprotection Enhances Adaptation of E. coli PNP for Herpes Simplex Virus-Based Glioma Therapy

Bharara, Suman, Sorscher, Eric J., Gillespie, G. Yancey, Lindsey, J. Russell, Hong, Jeong S., Curlee, Kimberly V., Allan, Paula W., Gadi, V.K., Alexander, Sherrie A., Secrist, John A., Parker, William

Journal:

Human Gene Therapy

Year:

2005

Language:

english

File:

PDF, 140 KB

english, 2005

43

Genetic Modification of Adeno-Associated Viral Vector Type 2 Capsid Enhances Gene Transfer Efficiency in Polarized Human Airway Epithelial Cells

White, April F., Mazur, Marina, Sorscher, Eric J., Zinn, Kurt R., Ponnazhagan, Selvarangan

Journal:

Human Gene Therapy

Year:

2008

Language:

english

File:

PDF, 264 KB

english, 2008

44

Gene Therapy for Cystic Fibrosis Using Cationic Liposome Mediated Gene Transfer: A Phase I Trial of Safety and Efficacy in the Nasal Airway. University of Alabama at Birmingham, Birmingham, Alabama

Sorscher, Eric J., Logan, James J., Frizzell, Raymond A., Lyrene, Raymond K., Bebok, Zsuzsa, Dong, J. Y., Duvall, M. D., Feigner, P. L., Matalon, Sadis, Walker, Lynn, Wiatrak, Brian J.

Journal:

Human Gene Therapy

Year:

1994

Language:

english

File:

PDF, 1.85 MB

english, 1994

45

Porcine nasal epithelial cultures for studies of cystic fibrosis sinusitis

Dean, Nichole, Ranganath, Neel K., Jones, Brandon, Zhang, Shaoyan, Skinner, Daniel, Rowe, Steven M., Sorscher, Eric J., Woodworth, Bradford A.

Journal:

International Forum of Allergy & Rhinology

Year:

2014

Language:

english

File:

PDF, 784 KB

english, 2014

46

18. Comparison of Antitumor Activity of Cytosine Deaminase::Uracil Phosphoribosyl Transferase (CD::UPRT) and Purine Nucleoside Phosphorylase (PNP) Suicide Genes Using Replicative but Non-Disseminative Adenovirus Vectors

Jaime, Jairo, Jabbour, Nadine, Parker, William, Sorscher, Eric, Nalbantoglu, Josephine, Massie, Bernard

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 83 KB

english, 2006

47

A Breath of Fresh Air

Rowe, Steven M., Clancy, J. P., Sorscher, Eric J.

Journal:

Scientific American

Year:

2011

Language:

english

File:

PDF, 1.65 MB

english, 2011

48

Efficient Intracellular Processing of the Endogenous Cystic Fibrosis Transmembrane Conductance Regulator in Epithelial Cell Lines

Varga, Károly, Jurkuvenaite, Asta, Wakefield, John, Hong, Jeong S., Guimbellot, Jennifer S., Venglarik, Charles J., Niraj, Ashutosh, Mazur, Marina, Sorscher, Eric J., Collawn, James F., Bebök, Zsuzsa

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 865 KB

english, 2004

49

PNP Anticancer Gene Therapy

Zhang, Yang, Parker, William, Sorscher, Eric, Ealick, Steven

Journal:

Current Topics in Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 519 KB

english, 2005

50

S-palmitoylation regulates biogenesis of core glycosylated wild-type and F508del CFTR in a post-ER compartment

McClure, Michelle L., Wen, Hui, Fortenberry, James, Hong, Jeong S., Sorscher, Eric J.

Journal:

Biochemical Journal

Year:

2014

Language:

english

File:

PDF, 1.18 MB

english, 2014